Chemotherapy and Hair Loss

Frequency of Sodium Valproate-Induced Hair Loss and Curly Hair

Sodium valproate has been widely used by man as an antiepileptic drug. Hair loss and curly hair is a rare side effect of sodium valproate. We have conducted a prospective clinical study in the Department of Neurology in Shafa Hospital, Kerman, Iran for ten years (1994-2004). All 211 epileptic patients in our study were given sodium valproate as a single drug treatment. During the course of ther...

p53 is essential for chemotherapy-induced hair loss.

Anticancer drugs stimulate apoptosis in the hair follicles (HF) and cause hair loss, the most common side effect of chemotherapy. In a mouse model for chemotherapy-induced hair loss, we demonstrate that p53 is essential for this process: in contrast to wild-type mice, p53-deficient mice show neither hair loss nor apoptosis in the HF keratinocytes that maintained active proliferation after cyclo...

Prevention of chemotherapy-induced hair loss by scalp cooling.

BACKGROUND Chemotherapy-induced temporary hair loss is one of the most common and distressing side-effects of cancer therapy. Scalp cooling to reduce this hair loss is a controversial issue for many doctors and nurses. This may be due to inadequate knowledge. METHODS This review from 53 publications and three personal communications focuses on the efficacy of the treatment, side-effects, poss...

Evaluation and treatment of male and female pattern hair loss

Diffuse hair loss in women in Ahwaz

Background: Diffuse hair loss is one of the most common complaints of women attending skin clinics. Objective: The purpose of this study was to evaluate diffuse hair loss in women referring to a private office. Patients and Methods: This descriptive, retrospective study was performed on women attending a private skin clinic in Ahwaz complaining of diffuse hair loss. The study was done for 10 mo...